Document Type : Review Article

Authors

1 Department of engineering,Kazerun Branch, Islamic Azad University, Kazeron, Iran

2 Department of engineering,Zarindasht Branch, Islamic Azad University, Zarindasht, Iran

Abstract

Accurate liver segmentation on Magnetic Resonance Images (MRI) is a challenging task especially at sites where surrounding tissues such as spleen and kidney have densities similar to that of the liver and lesions reside at the liver edges. The first and essential step for computer aided diagnosis (CAD) is the automatic liver segmentation that is still an open problem. Extensive research has been performed for liver segmentation; however it is still challenging to distinguish which algorithm produces more precise segmentation results to various medical images. In this paper, we have presented a new automatic system for liver segmentation in abdominal MRI images. Our method extracts liver regions based on several successive steps. The preprocessing stage is applied for image enhancement such as edge preserved and noise reduction. The proposed algorithm for liver segmentation is a combined algorithm which utilizes a contour algorithm with a Vector Field Convolution (VFC) field as its external force and perceptron neural network. By convolving the edge map generated from the image with the user-defined vector field kernel, VFC is calculated. We use trained neural networks to extract some features from liver region. The extracted features are used to find initial point for starting VFC algorithm. This system was applied to a series of test images to extract liver region. Experimental results showed the promise of the proposed algorithm.

Keywords

[1] P. Capadelli, E. Casiraghi, G. Lombardi, “Automatic liver segmentation from abdominal CT scans”, in: Proceedings of 14th International Conference on Image Analysis and Processing (ICIAP), 2007, pp.731-736.
[2] C. Bartolozzi, C.D. Pina, D. Cioni, L. Croceti, E. Batini, R. Lencioni, “Magnetic Resonance: Focal Liver Lesions Detection”, Characterization, Ablation, Medical Radiology, Springer, Berlin, 2005.
[3] C. Platero, J.M. Ponacela, P. Gonzalez, M.C. Tobary, J. Sanguino, G. Asensio, E. Santos, “Liver segmentation for hepatic lesions detection and characterization”, in: Proceedings of 5th IEEE International Symposium on Biomedical Imaging, 2008, pp. 13-16.
[4] V. Grau, A.U.J. Mewes, M. Alcaniz, R. Kikinis, S.K. Warfield, “Improved watershed transform for medical image segmentation using prior information”, IEEE Trans. Med. Imag., 23 (4) (2004) 447- 458.
[5] G. Chen, L. Gu, L. Qian, J. Xu, “An improved level set for liver segmentation and perfusion analysis in MRIs”, IEEE Trans. Image Process., 30 (1) (2009) 94-103.
[6] Z. Yuan, Y. Wang, J. Yang, Y. Liu, “A novel automatic liver segmentation technique for MR Images”, in: Proceedings of 3rd International Congress on Image and Signal Processing (CISP2010), 2010, pp. 1282-1286.
[7] S. Luo, Q. Hu, X. He, J. Li, J.S. Jin, M. Park, “Automatic liver parenchyma segmentation from abdominal CT images using support vector machines”, in: Proceedings of International Conference on Complex Medical Engineering (ICME), 2009, pp.1-5.
[8] X. Zhang, J. Tian, K. Deng, Y. Wu, X. Li, “Automatic liver segmentation using a statistical shape model with optimal surface detection”, IEEE Trans. Biomed. Eng., 57 (10) (2010) 2622-2626.
[9] H. Badakhshannoory, P. Saeedi, “A model-based validation scheme for organ segmentation in CT scan volumes”, IEEE Trans. Biomed. Eng., 58 (9) (2011) 2681–2693.
[10] H. Lamecker, T. Lange, M. Seebass, “Segmentation of the liver using a 3d statistical shape model”, Technical Report, Zuse Institue, Berlin (2004).
[11] L. Rusko, G. Bekes, M. Fidrich, “Automatic segmentation of the liver from multi- and single-phase contrast-enhanced CT images”, Med. Image Anal., 13 (6) (2009) 871-882.
[12] A.H. Foruzan, R.A. Zoroofi, M. Hori, Y. Sato, “A knowledge-based technique for liver segmentation in CT data”, Comp. Med. Imag. and Graph., 33 (8) (2009) 567-587.
[13] S.J. Lim, Y.Y. Jeong, Y.S. Ho, “Automatic liver segmentation for volume measurement in CT Images”, J. Vis. Commun. Image R., 17 (4) (2006) 860–875.
[14] L. Gao, D. Heath, B. Kuszyk, E. Fishman, “Automatic liver segmentation technique for three-dimensional visualization of CT data”, Radiology, 201 (1996) 359–364.
[15] F. Liu, B. Zhao, P. K. Kijewski, L. Wang, L. H. Schwartz, “Liver segmentation for CT images using GVF snake”, Med. Phys., 32 (12) (2005) 3699–3706.
[16] K.T. Bae, M.L. Giger, C.T. Chen, C. E. Kahn, “Automatic segmentation of liver structure in CT images”, Med. Phys., 20 (1) (1993) 71–78.
[17] E.L. Chen, P.C. Chung, C.L. Chen, H. M. Tsai, C.I. Chang, “An automatic diagnostic system for CT liver image classification”, IEEE Trans. Med. Imag., 22 (4) (2003) 483-492.
[18] J. Lee, N. Kim, H. Lee, J.B. Seo, H.J. Won, Y.M. Shin, Y.G. Shin, S.H. Kim, “Efficient liver segmentation using a level-set method with optimal detection of the initial liver boundary from level-set speed images”, Comput. Meth. Prog. Biomed., 88 (1) (2007) 26-38.
[19] Y. Zhao, Y. Zan, X. Wang, G. Li, “Fuzzy C-means clustering-based multilayer perceptron neural network for liver CT images automatic segmentation”, in: Proceedings of Control and Decision Conference (CCDC), 2010, pp. 3423-3427.
[20] M. Pham, R. Susomboon, T. Disney,D. Raicu, J. Furst, “A comparison of texture models for automatic liver segmentation”, in: Proceedings of the SPIE Medical Imaging 2007: Image Processing Conference, San Diego, CA, USA , February 2007.
[21] S. Geman and D. Geman, “Stochastic relaxation, gibbs distributions, and the bayesian restoration of images”, IEEE Trans. Pattern Anal. Mach. Intell., 6 (6) (1998) 721–741.
[22] N.H. Abdel-massieh, M.M. Hadhoud, K.A. Moustafa, “A fully automatic and efficient technique for liver segmentation from abdominal CT images”, in: Proceedings of the 7th International Conference on Informatics and Systems, May 2010, pp. 1-8.
[23] M. Kass, A.Witkin, D. Terzopolous, “Snake: Active contour models”, Int. J. Comp. Vision, 1 (4) (1987) 321-331.
[24] T. Chan, L.Vese, “Active contours without edges”, IEEE Trans. Image Process., 10 (2) (2001) 266–277.
[25] G. Chen, L. GU, “A novel liver perfusion analysis based on active contours and chamfer matching”, Medical Imaging and Augmented Reality (Lecture Notes in Computer Science 4091), Springer-Verlag, Berlin, Germany, 2006, pp.108–115.
[26] H. G. Barrow, J. M. Tenenbaum, R. C. Bolles, H. C. Wolf, “Parametric correspondence and chamfer matching: Two new techniques for image matching”, , in: Proceedings 5th Int. Joint Conf. Artif. Intell, 1997, pp. 659– 663.
[27] G. Borgefors, “Hierarchical chamfer matching: A parametric edge matching algorithm”, IEEE Trans. Pattern Anal. Mach. Intell., 10 (6) (1988) 849–865.
[28] O. Gloger, J. Kühn, A. Stanski, H. Völzke, R. Puls, “A fully automatic three-step liver segmentation method on LDA-based probability maps for multiple contrast MR images”, Magnetic Resonance Imaging, 28 (16) (2010) 882-897.
[29] I. Middleton, R. Damper, “Segmentation of magnetic resonance images using a combination of neural networks and active contour models”, Med. Eng. Phys., 26 (1) (2004) 71-86.
[30] Li, B. and Acton, S.T. “Active contour external force using vector field convolution for image segmentation”. IEEE Transactions on Image Processing 16,pp: 2096-2106 ,2007
[31] R.C.Gonzalez and R.E. Woods. Digital Image Processing, 2nd. Ed.Prentice-Hall,2002
[32] J. Awad, T.K. Abdel-Galil, M.M.A. Salama, A. Fenster, K. Rizkalla, and D.B. Downey, “Prostate’s boundary detection in transrectal ultrasound images using scanning technique”, IEEE CCECE,2003, pp: 1199–1202.
[33] Martin T.Hagan, Howard B.Dcmuth, Mark Beale: Neural Network Design, 2002.
[34] M. Kass, A. Witkin, and D. Terzopoulos, “Snakes: Active contour models”, International Journal of Computer Vision, vol. 1, no. 4, pp. 321-331, 1987
[35] Xu, Jerry L. Prince, “Snakes, Shapes, and Gradient Vector Flow”, IEEE Trans. Image Processing, 7 (36) (1998), pp: 359–369.
[36] D. Yuan and S. Lu, “Simulated static electric field (SSEF) snake for deformable models”, in International Conference on Pattern Recognition, Quebec, Canada, 2002.